It’S SKIN - Glutathione Shot B3 Anti Discoloration Serum Review

Tuesday, September 2, 2025

It’S SKIN - Glutathione Shot B3 Anti Discoloration Serum Review


Our skin tells the story of everything it’s been through, from acne scars and sun exposure to freckles and hyperpigmentation. Personally, I’ve struggled with dark spots from acne scars for years, and I’m always curious when I come across a serum that promises to help even out the skin tone and bring back some brightness.

A few months ago, I received the It’S SKIN Glutathione Shot B3 Anti Discoloration Serum as PR from the brand. There was no obligation to share my thoughts, but after using it consistently, I felt it was worth writing about, especially since it’s one of the more affordable brightening serums I’ve tried.


This post contains affiliate links. If you decide to purchase through my YesStyle code SWEET07 or Stylevana code INF10SWEET, I may earn a small commission at no extra cost to you.


What Is It'S SKIN Glutathione Shot B3 Anti Discoloration Serum?


As the name suggests, this serum is designed to target discoloration, uneven skin tone, and dullness. It’S SKIN has created it as part of their “Shot” line of serums, each one focusing on a specific skin concern. The Glutathione Shot B3 is all about brightening the skin and reducing the appearance of dark spots.

The formula combines some powerful ingredients:

  • Glutathione – a well-known antioxidant that helps brighten skin, reduce melanin production, and protect against environmental damage.
  • Niacinamide (Vitamin B3) – one of my favorite multitasking ingredients. It’s amazing for brightening, strengthening the skin barrier, reducing redness, and improving overall skin texture.
  • Tranexamic Acid – another popular brightening ingredient that helps fade stubborn hyperpigmentation and acne marks.
  • Adenosine – known for its skin-smoothing and anti-aging benefits.

This blend makes the serum gentle yet effective for targeting discoloration without being too harsh on sensitive skin.


My Experience Using the Serum


Like I mentioned, I’ve been testing this serum for a few months now. The first thing I noticed was the texture. It’s on the watery side but not completely clear, it has a milky, white appearance. It absorbs really quickly and doesn’t leave any stickiness behind, which I really appreciate since I like layering multiple products in my routine.

It does have a slight scent, but nothing strong or overpowering. I’m usually sensitive to fragrances in skincare, but this one didn’t irritate me or make me not want to use it. That was a big relief because some brightening serums can be too fragrant.

I used it both morning and night, and it layered well with my other skincare products. It never pilled under moisturizer or sunscreen, which makes it easy to add into any routine.

It’S SKIN - Glutathione Shot B3 Anti Discoloration Serum Review


Did It Work?


Yes, slowly but surely. After consistent use, I started noticing that my skin looked brighter overall. My freckles and dark spots didn’t disappear completely (that usually takes much longer and often needs stronger treatments), but they did start to fade a little bit.

What I really liked is that the serum is gentle. It didn’t cause any irritation, breakouts, or sensitivity, something that’s important for me since my skin reacts easily. Right after applying, my skin felt hydrated and normal, not tight or greasy.


How to Use It in Your Routine


This serum is versatile, but there are a few things to keep in mind when using it:


✅ Can be used with: moisturizers, hydrating serums (like hyaluronic acid), ceramides, and sunscreen. These will complement the brightening effects and help protect your skin barrier.

⚠️ Avoid layering with: high concentrations of vitamin C, exfoliating acids (like AHA/BHA), or retinol in the same routine. Mixing too many strong actives can increase irritation and actually damage the skin barrier.

Personally, I liked using it in the morning under sunscreen. Since glutathione and niacinamide both have antioxidant properties, they help boost your skin’s protection during the day.


Price and Value


Here’s where I think this serum really shines, the price. It’s around $15 on YesStyle, which makes it one of the most affordable brightening serums I’ve seen with this kind of ingredient list.

When you compare it to other serums that claim to do the same thing but cost $30–$50, this one feels like a no-brainer if you’re just starting out with brightening skincare. 

Plus, you can save even more with my discount codes: SWEET07 (YesStyle) or INF10SWEET (Stylevana).

Final Thoughts – Is It Worth Trying?


If you’re struggling with discoloration, acne scars, or just want to brighten your overall complexion without spending too much, I think the It’S SKIN Glutathione Shot B3 Anti Discoloration Serum is definitely worth trying.

It’s gentle, budget-friendly, and has a solid formula packed with proven ingredients like glutathione, niacinamide, and tranexamic acid. While it’s not an overnight miracle for dark spots, with consistent use it can absolutely help improve skin tone and brightness.

I will definitely continue using it in my routine. For me, the best thing about this serum is that it makes my skin look more radiant without causing irritation, and that’s something I value a lot.

Would I recommend it? Yes, especially if you’re looking for an affordable, beginner-friendly brightening serum. Just remember to be consistent and always pair it with a good sunscreen.

✨ Have you tried any glutathione-based skincare before? I’d love to hear about your experience in the comments!


 


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